Retrospective evaluation of PET-MRI registration algorithms

Shan, Zuyao Y., Mateja, Sara J., Reddick, Wilburn E., Glass, John O. and Shulkin, Barry L. (2011) Retrospective evaluation of PET-MRI registration algorithms. Journal of Digital Imaging, 24 3: 485-493. doi:10.1007/s10278-010-9300-y

Author Shan, Zuyao Y.
Mateja, Sara J.
Reddick, Wilburn E.
Glass, John O.
Shulkin, Barry L.
Title Retrospective evaluation of PET-MRI registration algorithms
Journal name Journal of Digital Imaging   Check publisher's open access policy
ISSN 0897-1889
Publication date 2011-06
Year available 2010
Sub-type Article (original research)
DOI 10.1007/s10278-010-9300-y
Volume 24
Issue 3
Start page 485
End page 493
Total pages 9
Place of publication New York, NY, United States
Publisher Springer New York
Collection year 2012
Language eng
Formatted abstract
The purpose of this study is to evaluate the accuracy of registration positron emission tomography (PET) head images to the MRI-based brain atlas. The [18F]fluoro-2-deoxyglucose PET images were normalized to the MRI-based brain atlas using nine registration algorithms including objective functions of ratio image uniformity (RIU), normalized mutual information (NMI), and normalized cross correlation (CC) and transformation models of rigid-body, linear, affine, and nonlinear transformations. The accuracy of normalization was evaluated by visual inspection and quantified by the gray matter (GM) concordance between normalized PET images and the brain atlas. The linear and affine registration based on the RIU provided the best GM concordance (average similarity index of 0.71 for both).We also observed that the GM concordances of linear and affine registration were higher than those of the rigid and nonlinear registration among the methods evaluated.
Keyword Normalization
Tissue concordance
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Part of the study has been presented on ISMRM 17th annual meeting. ; Online publication 1 May 2010

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
Centre for Advanced Imaging Publications
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