Modification of endometrial fatty acid concentrations by the pre-implantation conceptus in pasture-fed dairy cows

Meier, Susanne, Walker, Caroline G., Mitchell, Murray D., Littlejohn, Mathew D. and Roche, John R. (2011) Modification of endometrial fatty acid concentrations by the pre-implantation conceptus in pasture-fed dairy cows. Journal of Dairy Research, 78 3: 263-269. doi:10.1017/S0022029911000173


Author Meier, Susanne
Walker, Caroline G.
Mitchell, Murray D.
Littlejohn, Mathew D.
Roche, John R.
Title Modification of endometrial fatty acid concentrations by the pre-implantation conceptus in pasture-fed dairy cows
Journal name Journal of Dairy Research   Check publisher's open access policy
ISSN 0022-0299
1469-7629
Publication date 2011-08
Sub-type Article (original research)
DOI 10.1017/S0022029911000173
Volume 78
Issue 3
Start page 263
End page 269
Total pages 7
Place of publication Cambridge, England, U.K.
Publisher Cambridge University Press
Collection year 2012
Language eng
Formatted abstract
The current study determined whether the pre-implantation conceptus modified endometrial fatty acid concentrations. Oestrus was synchronized in 14 mature lactating cows and embryos were transferred on day 7. Cows were slaughtered 10 d later, with each uterine horn flushed, the pre-implantation conceptus located, and inter-caruncular endometrial tissue collected from the gravid horn (containing the pre-implantation conceptus) and non-gravid horn. Endometrial fatty acid concentrations in the gravid and non-gravid horn were compared using linear models in restricted maxiumum likelihood. Investigations of the correlations among selected fatty acids and trophoblast weight or uterine fluid interferon-tau (IFN-τ) concentrations were also undertaken. The presence of the pre-implantation conceptus had relatively minor effects on endometrial fatty acid concentrations, but the ω6:ω3 ratio was greater and concentrations of stearic and oleic acid were slightly increased in the gravid horn. In the gravid horn, a negative linear relationship between the concentration of arachidonic acid and conceptus weight and IFN- τconcentration in the uterine luminal fluid were observed. In contrast, there was a positive relationship between concentrations of dihomo-γ- linolenic acid in the non-gravid horn and conceptus weight. In conclusion, the presence of the pre-implantation conceptus appears to modulate endometrial fatty acids, as indicated by the differences in endometrial fatty acid concentrations in the gravid and non-gravid uterine horns. The physiological implication of these local effects of the pre-implantation conceptus, on reproductive success requires further investigation.
Keyword Uterus
Endometrium
Gravid
Non-gravid
Fatty Acid
Bovine
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2012 Collection
 
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Citation counts: TR Web of Science Citation Count  Cited 6 times in Thomson Reuters Web of Science Article | Citations
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