Central nervous system control of cough: pharmacological implications

Mazzone, Stuart B., McGovern, Alice E., Cole, Leonie J. and Farrell, Michael J. (2011) Central nervous system control of cough: pharmacological implications. Current Opinion in Pharmacology, 11 3: 265-271. doi:10.1016/j.coph.2011.05.005


Author Mazzone, Stuart B.
McGovern, Alice E.
Cole, Leonie J.
Farrell, Michael J.
Title Central nervous system control of cough: pharmacological implications
Journal name Current Opinion in Pharmacology   Check publisher's open access policy
ISSN 1471-4892
1471-4973
Publication date 2011-06-11
Sub-type Article (original research)
DOI 10.1016/j.coph.2011.05.005
Volume 11
Issue 3
Start page 265
End page 271
Total pages 7
Place of publication London, United Kingdom
Publisher Elsevier
Collection year 2012
Language eng
Abstract For many years the idea of a cough center in the brain dominated discussions in the field without any substantial progress in defining what this cough center is or how it functions. Substantial progress has now been made and many of the central neural elements involved in coughing are being described. Furthermore, hypothesis driven research into the function of these neural elements is providing exciting new leads for possible therapeutic targets. The concept of a specific, centrally acting drug for cough suppression is fast becoming a reality. This review summarizes the key findings from the past few years and provides a perspective on future directions for the development of novel antitussives.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
School of Biomedical Sciences Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 26 Aug 2011, 09:24:22 EST by Dr Stuart Mazzone on behalf of School of Biomedical Sciences