Mouse whole-body organ mapping by non-rigid registration approach

Xiao, Di, Zahra, David, Bourgeat, Pierrick, Berghofer, Paula, Tamayo, Oscar Acosta, Green, Heather, Gregoire, Marie Claude and Salvado, Olivier (2011). Mouse whole-body organ mapping by non-rigid registration approach. In: Proceedings of SPIE: Progress in Biomedical Optics and Imaging. Medical Imaging 2011 - Biomedical Applications in Molecular, Structural, and Functional Imaging, Florida, United States, (79650E.1-79650E.7). 13-16 February 2011. doi:10.1117/12.877921

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Author Xiao, Di
Zahra, David
Bourgeat, Pierrick
Berghofer, Paula
Tamayo, Oscar Acosta
Green, Heather
Gregoire, Marie Claude
Salvado, Olivier
Title of paper Mouse whole-body organ mapping by non-rigid registration approach
Conference name Medical Imaging 2011 - Biomedical Applications in Molecular, Structural, and Functional Imaging
Conference location Florida, United States
Conference dates 13-16 February 2011
Proceedings title Proceedings of SPIE: Progress in Biomedical Optics and Imaging   Check publisher's open access policy
Journal name Medical Imaging 2011: Biomedical Applications in Molecular, Structural, and Functional Imaging   Check publisher's open access policy
Place of Publication Bellingham, WA, United States
Publisher S P I E - International Society for Optical Engineering
Publication Year 2011
Sub-type Fully published paper
DOI 10.1117/12.877921
Open Access Status File (Publisher version)
ISBN 978-0-81948-507-6
ISSN 0277-786X
1996-756X
Volume 7965
Start page 79650E.1
End page 79650E.7
Total pages 7
Collection year 2012
Language eng
Abstract/Summary Automatic small animal whole-body organ registration is challenging because of subject's joint structure, posture and position difference and loss of reference features. In this paper, an improved 3D shape context based non-rigid registration method is applied for mouse whole-body skeleton registration and lung registration. A geodesic path based non-rigid registration method is proposed for mouse torso skin registration. Based on the above registration methods, a novel non-rigid registration framework is proposed for mouse whole-body organ mapping from an atlas to new scanned CT data. A preliminary experiment was performed to test the method on lung and skin registration. A whole-body organ mapping was performed on three target data and the selected organs were compared with the manual outlining results. The robust of the method has been demonstrated.
Keyword Non-rigid registration
Mouse whole-body organ mapping
Ct Data
Atlas
Q-Index Code E1
Q-Index Status Confirmed Code
Institutional Status Non-UQ

 
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