Novel applications of locked nucleic acids

Veedu, Rakesh N., Vester, Birte and Wengel, Jesper (2007). Novel applications of locked nucleic acids. In: Nucleic Acids Symposium Series (2004). Fifth International Symposium on Nucleic Acids Chemistry, Osaka, Japan, (29-30). 20-22 November 2007. doi:10.1093/nass/nrm015

Author Veedu, Rakesh N.
Vester, Birte
Wengel, Jesper
Title of paper Novel applications of locked nucleic acids
Conference name Fifth International Symposium on Nucleic Acids Chemistry
Conference location Osaka, Japan
Conference dates 20-22 November 2007
Proceedings title Nucleic Acids Symposium Series (2004)   Check publisher's open access policy
Journal name Nucleic Acids Symposium Series   Check publisher's open access policy
Place of Publication Oxford, United Kingdom
Publisher Oxford University Press
Publication Year 2007
Sub-type Fully published paper
DOI 10.1093/nass/nrm015
Open Access Status
ISSN 1746-8272
Volume 51
Issue 1
Start page 29
End page 30
Total pages 2
Language eng
Abstract/Summary Locked Nucleic Acid (LNA) nucleoside triphosphates were prepared and their substrate properties for different polymerases during primer extension and PCR experiments investigated. Phusion High Fidelity DNA polymerase and 9( degrees )Nm(TM) DNA polymerase readily accept LNA nucleoside 5'-triphosphates as substrates in primer extension assays. However, in PCR assays, However, in PCR assays, DNA 9oN(m) polymerase proved to be the best for amplification employing the LNA-A nucleotide.
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Conference Paper
Collection: School of Chemistry and Molecular Biosciences
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Created: Thu, 18 Aug 2011, 14:28:51 EST by Dr Rakesh Naduvile Veedu on behalf of School of Chemistry & Molecular Biosciences