Peptide-based subunit nanovaccines

Skwarczynski, Mariusz and Toth, Istvan (2011) Peptide-based subunit nanovaccines. Current Drug Delivery, 8 3: 282-289. doi:10.2174/156720111795256192

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Author Skwarczynski, Mariusz
Toth, Istvan
Title Peptide-based subunit nanovaccines
Journal name Current Drug Delivery   Check publisher's open access policy
ISSN 1567-2018
1875-5704
Publication date 2011-05
Sub-type Critical review of research, literature review, critical commentary
DOI 10.2174/156720111795256192
Volume 8
Issue 3
Start page 282
End page 289
Total pages 8
Place of publication Bussum, Netherlands
Publisher Bentham Science Publishers
Collection year 2012
Language eng
Abstract Classical vaccines incorporating live or attenuated microorganisms possess several disadvantages and cannot be applied against cancer and some pathogens. Modern vaccines utilizing immunogenic subunits derived from a particular pathogen are able to overcome these obstacles but need a specific delivery system for their efficacy. Nanotechnology has opened a new window into these delivery methodologies. A nano-sized formulation of subunit vaccines has been proven to be very effective in inducing cellular and humoral immune responses. Here, we review a number of peptide vaccine delivery strategies based on nanoparticles composed of polymers, peptides, lipids, and inorganic materials.
Keyword Subunit vaccine
Peptide epitope
Nanotechnology
Nanoparticles
Infectious diseases
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Non HERDC
ERA White List Items
School of Chemistry and Molecular Biosciences
 
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Created: Mon, 04 Jul 2011, 14:23:53 EST by Dr Mariusz Skwarczynski on behalf of School of Chemistry & Molecular Biosciences