Amiodarone for post-operative junctional ectopic tachycardia

Plumpton, Kevin, Justo, Robert and Haas, Nikolaus (2005) Amiodarone for post-operative junctional ectopic tachycardia. Cardiology in the Young, 15 1: 13-18. doi:10.1017/S1047951105000041

Author Plumpton, Kevin
Justo, Robert
Haas, Nikolaus
Title Amiodarone for post-operative junctional ectopic tachycardia
Journal name Cardiology in the Young   Check publisher's open access policy
ISSN 1047-9511
Publication date 2005-02
Sub-type Article (original research)
DOI 10.1017/S1047951105000041
Volume 15
Issue 1
Start page 13
End page 18
Total pages 6
Place of publication Cambridge, United Kingdom
Publisher Cambridge University Press
Language eng
Formatted abstract
Post-operative junctional ectopic tachycardia is a transient, but potentially life threatening, rapid automatic tachyarrhythmia that requires urgent and adequate treatment. In our study, we review retrospectively the use and efficacy of amiodarone for this arrhythmia over an 8-year period in our institution.

Methods and patients:
Retrospective review revealed 15 patients who were administered amiodarone for postoperative junctional ectopic tachycardia during the period. The median age was 2.6 months, with a range from 8 days to 8.1 months. The median weight was 4.6 kilograms, with a range from 2.6 to 8.2 kilograms.

he median heart rate at diagnosis of the tachycardia was 192 beats per minute, and the range was 182 to 229 beats per minute. The biochemistry was essentially normal. The median length of time until the tachycardia was controlled was 4.5 hours, and the range was from 1 to 19.5 hours, with 13 of the 15 patients controlled within 12 hours. The median dose of amiodarone received by this time was 5.9 milligrams per kilogram, with a range from 1.0 to 25.0 milligrams per kilogram. Hypotension or bradycardia within 4 hours of commencing amiodarone were noted in 2 patients.

Experience in our institution, and a review of the literature, suggests that the most rapid control of post-operative junctional ectopic tachycardia will be obtained by a bolus of amiodarone followed by an intravenous infusion. Intravenous amiodarone is generally safe, with few side effects. Reported life threatening arrhythmias, however, suggest that intravenous amiodarone should be restricted to a setting where invasive monitoring and external cardiac pacing are available.
Keyword Congenital heart disease
Paediatric intensive care
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Faculty of Health and Behavioural Sciences -- Publications
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Citation counts: TR Web of Science Citation Count  Cited 13 times in Thomson Reuters Web of Science Article | Citations
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