The human SOX11 gene: Cloning, chromosomal assignment and tissue expression

Jay, Philippe, Marsollier, Catherine, Taviaux, Sylvie, Hardelin, Jean-Pierre, Koopman, Peter and Berta, Phillipe (1995) The human SOX11 gene: Cloning, chromosomal assignment and tissue expression. Genomics, 29 2: 541-545. doi:10.1006/geno.1995.9970

Author Jay, Philippe
Marsollier, Catherine
Taviaux, Sylvie
Hardelin, Jean-Pierre
Koopman, Peter
Berta, Phillipe
Title The human SOX11 gene: Cloning, chromosomal assignment and tissue expression
Journal name Genomics   Check publisher's open access policy
ISSN 0888-7543
Publication date 1995-09
Sub-type Article (original research)
DOI 10.1006/geno.1995.9970
Volume 29
Issue 2
Start page 541
End page 545
Total pages 5
Place of publication Maryland Heights, MO, United States
Publisher Academic Press
Language eng
Abstract The mammalian testis determining gene SRY contains an HMG box-related DNA binding motif. By analogy a family of genes related to SRY in the HMG domain have been called SOX (SRY box-related genes). We have cloned and characterized the human SOX11 gene using the partial cloning of both human and mouse SOX11 genes and mapped it to chromosome 2p25. The SOX11 sequence is strongly conserved with the chicken homologue and is related to SOX4. It contains several putative transcriptional either activator or repressor domains. SOX11 expression pattern is consistent with the hypothesis that this gene is important in the developing nervous system.
Keyword Sex-determining region
Dna-binding motif
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Institute for Molecular Bioscience - Publications
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