Parathyroid hormone related protein in hypercalcaemia of Hodgkin's disease

Bolodeoku, J., Lakhani, S., Dunne, F., Ratcliffe, W. A., Clarke, M. and Barron, J. L. (1992) Parathyroid hormone related protein in hypercalcaemia of Hodgkin's disease. Journal of Clinical Pathology, 45 6: 541-542. doi:10.1136/jcp.45.6.541


Author Bolodeoku, J.
Lakhani, S.
Dunne, F.
Ratcliffe, W. A.
Clarke, M.
Barron, J. L.
Title Parathyroid hormone related protein in hypercalcaemia of Hodgkin's disease
Journal name Journal of Clinical Pathology   Check publisher's open access policy
ISSN 0021-9746
1472-4146
Publication date 1992-06
Sub-type Other
DOI 10.1136/jcp.45.6.541
Volume 45
Issue 6
Start page 541
End page 542
Total pages 2
Place of publication B M J Group
Publisher London, United Kingdom
Language eng
Abstract The role of parathyroid hormone related protein (PTHRP) as a humoral mediator of hypercalcaemia was investigated in a patient with lymphocyte depleted Hodgkin's disease during an episode of hypercalcaemia, using an immunohistochemical staining technique for PTHRP on the tumour tissue and an immunoradiometric (IRMA) assay for PTHRP1-86 on the patient's plasma. The plasma PTHRP was less than 0.23 pmol/l in the range found in normocalcaemic controls, and the immunohistochemical staining was not positive for protein. PTHRP did not have a role in the pathogenesis of hypercalcaemia in this patient.
Keyword Humoral Hypercalcemia
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Other
Collection: School of Medicine Publications
 
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