Is there a benign to malignant progression?

Lakhani, S. R. (1997). Is there a benign to malignant progression?. In: 2nd International Meeting on Current Topics in Breast Cancer Research, Cambridge, England, (93-104). Sep, 1996.

Author Lakhani, S. R.
Title of paper Is there a benign to malignant progression?
Conference name 2nd International Meeting on Current Topics in Breast Cancer Research
Conference location Cambridge, England
Conference dates Sep, 1996
Journal name Endocrine-Related Cancer   Check publisher's open access policy
Place of Publication Bristol, United Kingdom
Publisher BioScientifica
Publication Year 1997
Sub-type Fully published paper
ISSN 1351-0088
Volume 4
Issue 1
Start page 93
End page 104
Total pages 12
Language eng
Formatted Abstract/Summary
Introduction Within Western Europe and the United States, breast cancer is the commonest malignancy in women. It is estimated that approximately 1:12 women will develop the tumour in their life time. Each year within the UK, there are 25 000 new cases accounting for 19% of all newly diagnosed cancers. It is the leading cause of female cancer deaths (HMSO 1991). Despite innovations in diagnosis and treatment, the effect on mortality has been modest. A major contributory factor to this limited success has been the lack of understanding about the natural history of the disease.

The problems in managing advanced disease has focused attention on detecting 'early' disease with the use of mammographic screening. This has led to the increased detection of preinvasive disease, particularly ductal carcinoma in situ (DCIS) (Molloy et al. 1989, Evans et al. 1994). This changing pattern of disease encountered by histopathologists has highlighted many deficiencies
Keyword Human-breast-cancer
Carcinoma in-situ
Comparative genomic hybridization
Polymerase chain-reaction
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Conference Paper
Collection: Faculty of Health and Behavioural Sciences -- Publications
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