Therapy for disseminatedcoccidioidomycosis with transferfactor from arelateddonor

Steele, R. W., Sieger, B. E., McNitt, T. R., Gentry, L. O. and Moore, W. L. (1976) Therapy for disseminatedcoccidioidomycosis with transferfactor from arelateddonor. American Journal of Medicine, 61 2: 283-286. doi:10.1016/0002-9343(76)90178-9

Author Steele, R. W.
Sieger, B. E.
McNitt, T. R.
Gentry, L. O.
Moore, W. L.
Title Therapy for disseminatedcoccidioidomycosis with transferfactor from arelateddonor
Journal name American Journal of Medicine   Check publisher's open access policy
ISSN 0002-9343
Publication date 1976-08
Sub-type Article (original research)
DOI 10.1016/0002-9343(76)90178-9
Volume 61
Issue 2
Start page 283
End page 286
Total pages 4
Place of publication Bridgewater, NJ, United States
Publisher Excerpta Medica
Language eng
Abstract A 17 year old Caucasian woman in whom disseminatedcoccidioidomycosis developed with culture positive meningitis during her third trimester of pregnancy was treated with amphotericin B and subsequently with transferfactor prepared from her father's peripheral lymphocytes. Clinical response and in vivo and in vitro immunologic data indicated that this transferfactor afforded a significant contribution to her survival whereas previous therapy with transferfactor from an unrelated donor provided only transient immunologic reactivity. This experience suggests that transferfactor prepared from arelateddonor with positive responses to C. immitis may be more efficacious than that prepared from an unrelated donor.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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