Screening for cell mediated immunity in children

Steele, R. W., Suttle, D. E., Lemaster, P. C. and Patterson, F. D. (1976) Screening for cell mediated immunity in children. American Journal of Diseases of Children, 130 11: 1218-1221.

Author Steele, R. W.
Suttle, D. E.
Lemaster, P. C.
Patterson, F. D.
Title Screening for cell mediated immunity in children
Journal name American Journal of Diseases of Children   Check publisher's open access policy
ISSN 0002-922X
Publication date 1976
Sub-type Article (original research)
Volume 130
Issue 11
Start page 1218
End page 1221
Total pages 4
Place of publication Chicago, IL, United States
Publisher American Medical Association
Language eng
Abstract Skin testing and in vitro lymphocyte blastogenesis with Monilia and tetanus toxoid were examined as methods of screening cell mediated immunity (CMI) in infants and children. With increasing age, all assays were more likely to be positive. Tetanus toxoid was a better single screening antigen than Monilia, particularly for young infants. Combining all assays, at least one was positive in 88% of children over 6 weeks of age. Combining the two skin tests, at least one was positive in 73% of children in the same age range. Results for the blastogenic assays indicated that this in vitro test is more sensitive than the in vivo skin test for demonstrating CMI to these two antigens. Infants with documented histories for Monilia diaper rash had a significantly higher probability of having a positive skin or blastogenic reaction with Monilia.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Journal title since 1994: Archives of Pediatrics and Adolescent Medicine (1072-4710; 1538-3628)

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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