Psychologic modulation of the human immune response to varicella zoster

Smith Jr., G. R., McKenzie, J. M., Marmer, D. J. and Steele, R. W. (1985) Psychologic modulation of the human immune response to varicella zoster. Archives of Internal Medicine, 145 11: 2110-2112. doi:10.1001/archinte.1985.00360110186036

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Author Smith Jr., G. R.
McKenzie, J. M.
Marmer, D. J.
Steele, R. W.
Title Psychologic modulation of the human immune response to varicella zoster
Journal name Archives of Internal Medicine   Check publisher's open access policy
ISSN 0003-9926
Publication date 1985
Sub-type Article (original research)
DOI 10.1001/archinte.1985.00360110186036
Open Access Status File (Publisher version)
Volume 145
Issue 11
Start page 2110
End page 2112
Total pages 3
Place of publication Chicago, IL, United States
Publisher American Medical Association
Language eng
Abstract Psychoimmunology, the interrelationship between the brain/mind/psyche and the immune system, is now an established area of scientific research. Based on prior investigations we hypothesized that an experienced meditator could affect her delayed hypersensitivity reaction by a psychological process. A single-case study design was employed in which the subject was skin tested weekly with varicella zoster skin test reagent. After baseline immunologic studies, she was able, as hypothesized, to significantly reduce both the induration of her delayed hypersensitivity skin test reaction and in vitro lymphocyte stimulation to varicella zoster. Then, as predicted, she was able to allow her reaction to return to baseline. As a confirmation of what is to our knowledge this previously undescribed phenomenon, she was able to reproduce the entire sequence nine months later. It appears that this subject can intentionally modulate her immune response by a psychologic mechanism.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 30 times in Thomson Reuters Web of Science Article | Citations
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