Bacterial-meningitis presenting with normal cerebrospinal-fluid

Polk, D. B. and Steele, R. W. (1987) Bacterial-meningitis presenting with normal cerebrospinal-fluid. Pediatric Infectious Disease Journal, 6 11: 1040-1042.

Author Polk, D. B.
Steele, R. W.
Title Bacterial-meningitis presenting with normal cerebrospinal-fluid
Journal name Pediatric Infectious Disease Journal   Check publisher's open access policy
ISSN 0891-3668
Publication date 1987-11
Sub-type Article (original research)
Volume 6
Issue 11
Start page 1040
End page 1042
Total pages 3
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Language eng
Abstract At a large children's hospital cases of bacterial meningitis with normal initial cerebrospinal fluid determinations other than culture or antigen detection assays were reviewed in an attempt to determine clinical or other laboratory findings accompanying this presentation. During a 5-year period from January, 1980, through December, 1985, 7 of 261 pediatric meningitis patients (2.7%) fulfilled these criteria. Ages ranged from 3 weeks to 18 months. All 7 patients were hospitalized for observation with all but 1 begun on empiric antibiotic therapy. Laboratory parameters such as a complete blood count, sedimentation rate or C-reactive protein did not influence decisions for management. Cerebrospinal fluid antigen detection assays were negative in all but one patient with pneumococcal meningitis. Review of these cases did not reveal unique indicators for bacterial meningitis. The results emphasize that the physician must rely on clinical judgment in initiating empiric antimicrobial therapy once apparently normal cerebrospinal fluid parameters are observed.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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