Split liver transplantation

Yersiz, H., Cameron, A. M., Carmody, I., Zimmerman, M. A., Kelly, B. S., Ghobrial, R. M., Farmer, D. G. and Busuttil, R. W. (2006). Split liver transplantation. In: Mehmet A. Haberal, 8th Meeting of the Turkish Transplantation Society, Ankara, Turkey, (602-603). Jun 22-24 2005. doi:10.1016/j.transproceed.2005.12.064

Author Yersiz, H.
Cameron, A. M.
Carmody, I.
Zimmerman, M. A.
Kelly, B. S.
Ghobrial, R. M.
Farmer, D. G.
Busuttil, R. W.
Title of paper Split liver transplantation
Conference name 8th Meeting of the Turkish Transplantation Society
Conference location Ankara, Turkey
Conference dates Jun 22-24 2005
Journal name Transplantation Proceedings   Check publisher's open access policy
Place of Publication Philadelphia, PA, United States
Publisher Elsevier
Publication Year 2006
Sub-type Fully published paper
DOI 10.1016/j.transproceed.2005.12.064
ISSN 0041-1345
Editor Mehmet A. Haberal
Volume 38
Issue 2
Start page 602
End page 603
Total pages 2
Language eng
Abstract/Summary Seventy-five thousand Americans develop organ failure each year. Fifteen percent of those on the list for transplantation die while waiting. Several possible mechanisms to expand the organ pool are being pursued including the use of extended criteria donors, living donation, and split deceased donor transplants. Cadaveric organ splitting results from improved understanding of the surgical anatomy of the liver derived from Couinaud. Early efforts focused on reduced-liver transplantation (RLT) reported by both Bismuth and Broelsch in the mid-1980s. These techniques were soon modified to create both a left lateral segment graft appropriate for a pediatric recipient and a right trisegment for an appropriately sized adult. Techniques of split liver transplantation (SLT) were also modified to create living donor liver transplantation. Pichlmayr and Bismuth reported successful split liver transplantation in 1989 and Emond reported a larger series of nine split procedures in 1990. Broelsch and Busuttil described a technical modification in which the split was performed in situ at the donor institution with surgical division completed in the heart beating cadaveric donor. In situ splitting reduces cold ischemia, simplifies identification of biliary and vascular structures, and reduces reperfusion hemorrhage. However, in situ splits require specialized skills, prolonged operating room time, and increased logistical coordination at the donor institution. At UCLA over 120 in situ splits have been performed and this technique is the default when an optimal donor is available. Split liver transplantation now accounts for 10% of adult transplantations at UCLA and 40% of pediatric transplantations.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Conference theme: “Honoring the Work of lhsan Dogramacı.”

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