Chicken osteoclasts do not possess calcitonin receptors

Nicholson, G.C., Sexton, P.M. and Martin, T.J. (1987) Chicken osteoclasts do not possess calcitonin receptors. Journal of Bone and Mineral Research, 2 1: 53-59.

Author Nicholson, G.C.
Sexton, P.M.
Martin, T.J.
Title Chicken osteoclasts do not possess calcitonin receptors
Journal name Journal of Bone and Mineral Research   Check publisher's open access policy
ISSN 0884-0431
Publication date 1987-02
Sub-type Article (original research)
Volume 2
Issue 1
Start page 53
End page 59
Total pages 7
Place of publication Malden, MA, United States
Publisher Wiley-Blackwell Publishing
Language eng
Abstract Osteoclasts freshly isolated from embryonic chicks have been examined for calcitonin receptors using radio-iodine-labeled salmon calcitonin. Calcitonin binding to chick osteoclasts could not be shown by either autoradiography or biochemical binding studies. Furthermore, calcitonin did not stimulate cyclic AMP production. By contrast, rat osteoclasts have abundant calcitonin receptors, and a sensitive cyclic AMP response to calcitonin has been shown previously. It is concluded that chick osteoclasts do not possess calcitonin receptors, a finding which could explain the lack of calcitonin responsiveness observed in other avian osteoclast culture systems.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Article first published online: 3 December 2009.

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 56 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Tue, 24 May 2011, 14:56:32 EST by System User on behalf of Rural Clinical School