Kidney transplantation without reversal of warfarin

Mudge, David W., Campbell, Scott B. and Ray, Mark (2010) Kidney transplantation without reversal of warfarin. Nephrology, Dialysis and Transplantation Plus, 3 2: 170-171. doi:10.1093/ndtplus/sfp150

Author Mudge, David W.
Campbell, Scott B.
Ray, Mark
Title Kidney transplantation without reversal of warfarin
Journal name Nephrology, Dialysis and Transplantation Plus   Check publisher's open access policy
ISSN 1753-0784
Publication date 2010-04
Year available 2009
Sub-type Article (original research)
DOI 10.1093/ndtplus/sfp150
Volume 3
Issue 2
Start page 170
End page 171
Total pages 2
Place of publication United Kingdom
Publisher Oxford University Press
Collection year 2011
Language eng
Abstract Some patients called for kidney transplantation are anticoagulated with warfarin for indications such as antiphospholipid syndrome, where the risk of thrombosis with reversal may be high. Traditionally, the approach has been reversal of warfarin and treatment perioperatively with intravenous unfractionated heparin. However, this may be complicated by either thrombosis or bleeding if the heparin dose is incorrect. We report the case of a peritoneal dialysis patient warfarinized for antiphospholipid syndrome who was successfully transplanted with an international normalized ratio of 2.1 with neither thrombosis nor bleeding. This may be an alternative to heparin for patients in whom anticoagulation must be maintained. © 2009 The Author. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.
Keyword Anticoagulation
Antiphospholipid syndrome
Kidney transplantation
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Medicine Publications
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Created: Mon, 18 Apr 2011, 23:15:47 EST by Dr David Mudge on behalf of Surgery - Princess Alexandra Hospital