A Meta-Analytic Review of Verbal Fluency Deficits in Huntington’s Disease

Henry, Julie D., Crawford, John R. and Phillips, Louise H. (2005) A Meta-Analytic Review of Verbal Fluency Deficits in Huntington’s Disease. Neuropsychology, 19 2: 243-252. doi:10.1037/0894-4105.19.2.243


Author Henry, Julie D.
Crawford, John R.
Phillips, Louise H.
Title A Meta-Analytic Review of Verbal Fluency Deficits in Huntington’s Disease
Journal name Neuropsychology   Check publisher's open access policy
ISSN 0894-4105
Publication date 2005-03
Year available 2005
Sub-type Article (original research)
DOI 10.1037/0894-4105.19.2.243
Volume 19
Issue 2
Start page 243
End page 252
Total pages 10
Place of publication Washington DC, USA
Publisher American Psychological Association
Collection year 2006
Language eng
Formatted abstract
A meta-analysis of 30 studies with 1,511 participants was conducted to estimate and compare the magnitude of deficits on tests of phonemic and semantic fluency for patients with Huntington’s disease (HD) relative to healthy control participants. As has been found for patients with focal frontal cortical lesions (but not for patients with focal temporal cortical lesions), symptomatic HD patients were comparably impaired on tests of phonemic and semantic fluency (rs = .71 and .73, respectively). However, in contrast to patients with focal frontal lobe injuries, fluency deficits did not qualify as
differential deficits relative to verbal intelligence or psychomotor speed. Therefore, for patients with HD, deficits on tests of phonemic and semantic fluency do not appear to reflect executive dysfunction but a more generalized cognitive impairment.
Keyword Executive
Huntington's
Meta-analysis
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Psychology Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 41 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 43 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 18 Apr 2011, 14:25:09 EST by Lucy O'Brien on behalf of School of Psychology