Skin surfactant proteins: Presence and potential defense functions

Cross, Sheree E. (2010). Skin surfactant proteins: Presence and potential defense functions. In Nancy A. Monteiro-Riviere (Ed.), Toxicology of the skin (pp. 280-288) New York, NY, U.S.A.: Informa Healthcare USA. doi:10.3109/9781420079180.018

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Author Cross, Sheree E.
Title of chapter Skin surfactant proteins: Presence and potential defense functions
Title of book Toxicology of the skin
Place of Publication New York, NY, U.S.A.
Publisher Informa Healthcare USA
Publication Year 2010
Sub-type Research book chapter (original research)
DOI 10.3109/9781420079180.018
Series Target Organ Toxicology Series
ISBN 9781420079173
1420079174
9781420079180
1420079182
Editor Nancy A. Monteiro-Riviere
Volume number 29
Chapter number 18
Start page 280
End page 288
Total pages 9
Total chapters 27
Collection year 2011
Language eng
Formatted Abstract/Summary
For many years the barrier function of the skin has been considered to reside in the unique structural properties of the stratum corneum. However, this is only part of the story, as the skin's defense against its environment is biological as well as physical. The body's innate immune system evolved to first recognize pathogens and then eradicate them, a basic survival mechanism to prevent the host being overrun with microbial infections. Over 10 years ago, we were introduced to the concept that perhaps peptides with antimicrobial activities were also naturally present in the skin of humans.
© 2010 by Informa Healthcare USA, Inc.
Keyword Toxicology
Barrier
Skin
Toxicity
Q-Index Code B1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published under "Part II: Altered Barriers".

Document type: Book Chapter
Collections: Official 2011 Collection
School of Medicine Publications
 
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Created: Fri, 01 Apr 2011, 08:20:58 EST by Debbie Banks on behalf of Medicine - Princess Alexandra Hospital