The Prevention of Schizophrenia

Brown, Alan S. and McGrath, John J. (2011) The Prevention of Schizophrenia. Schizophrenia Bulletin, 37 2: 257-261. doi:10.1093/schbul/sbq122

Author Brown, Alan S.
McGrath, John J.
Title The Prevention of Schizophrenia
Journal name Schizophrenia Bulletin   Check publisher's open access policy
ISSN 0586-7614
Publication date 2011-03
Year available 2010
Sub-type Article (original research)
DOI 10.1093/schbul/sbq122
Volume 37
Issue 2
Start page 257
End page 261
Total pages 5
Editor William T. Carpenter
Place of publication Oxford, U.K
Publisher Oxford University Press
Collection year 2011
Language eng
Formatted abstract
A series of articles that speculate on the primary prevention of schizophrenia might seem overly optimistic, if not implausible. However, we do not share this degree of nihilism. Much has been learned about risk factors for schizophrenia over the last 3 decades. The incidence of schizophrenia varies between sites and over time. Some ethnic groups are at increased risk of schizophrenia when they migrate to particular counties but not in their country of origin. Almost certainly, these gradients are driven by environmentally mediated risk factors. It seems reasonable to expect that at least some of these exposures will be potentially modifiable. Epidemiologic research has revealed a range of candidate exposures related to infection and nutrition, which are reviewed in this volume (see Brown and Patterson, McGrath et al), as well as a host of other putative risk factors such as psychosocial stress, cannabis use, and advanced paternal age, and other exposures which, in our view, are worthy of careful scrutiny. The stage is now set for the “implausible”—the primary prevention of schizophrenia.
© The Author 2010. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved.
Keyword Cannabis use
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Advance Access publication on October 27, 2010.

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Created: Sun, 27 Mar 2011, 00:01:36 EST