Early menstrual characteristics associated with subsequent diagnosis of endometriosis

Treloar, Susan A., Bell, Tanya A., Nagle, Christina M., Purdie, David M. and Green, Adele C. (2010) Early menstrual characteristics associated with subsequent diagnosis of endometriosis. American Journal of Obstetrics and Gynecology, 202 6: 534.e1-534.e6. doi:10.1016/j.ajog.2009.10.857

Author Treloar, Susan A.
Bell, Tanya A.
Nagle, Christina M.
Purdie, David M.
Green, Adele C.
Title Early menstrual characteristics associated with subsequent diagnosis of endometriosis
Journal name American Journal of Obstetrics and Gynecology   Check publisher's open access policy
ISSN 0002-9378
Publication date 2010-06
Sub-type Article (original research)
DOI 10.1016/j.ajog.2009.10.857
Volume 202
Issue 6
Start page 534.e1
End page 534.e6
Total pages 6
Place of publication United States
Publisher Mosby, Inc.
Collection year 2011
Language eng
Formatted abstract
The aim of this study was to investigate the association between early menstrual characteristics, before symptom onset, and later diagnosis of endometriosis.

Study Design:

This was a case-control study of 268 Australian women with surgically confirmed moderate-to-severe endometriosis (cases) and 244 women without endometriosis (controls). Early menstrual cycle characteristics, before age at symptom onset, were analyzed.

Menarche after age 14 years was strongly and inversely associated with endometriosis (odds ratio, 0.3; 95% confidence interval, 0.1-0.6). A history of dysmenorrhea was associated with subsequent endometriosis (odds ratio, 2.6; 95% confidence interval, 1.1-6.2). Despite a suggestive trend, shorter menstrual cycle length was not associated with endometriosis. Duration of natural menstruation and heaviness of flow were not associated with subsequent risk of endometriosis; neither was the reported type of sanitary protection used nor history of sexual intercourse during menstruation.


There is a decreased risk of endometriosis with late age at menarche and an increased risk in women who report an early history of dysmenorrhea.
© 2010 Mosby, Inc. All rights reserved.
Keyword Dysmenorrhea
Early menstrual characteristics
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
Centre for Military and Veterans' Health Publications
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Created: Wed, 23 Mar 2011, 12:04:38 EST by Bev Ware on behalf of Centre for Australian Military & Veterans' Health