A randomised, assessor blind, parallel group comparative efficacy trial of three products for the treatment of head lice - melalueca oil and lavender oil, pyrethrins and piperonyl butoxide, and a "suffocation" product

Barker, Stephen C. and Altman, Phillip M. (2010) A randomised, assessor blind, parallel group comparative efficacy trial of three products for the treatment of head lice - melalueca oil and lavender oil, pyrethrins and piperonyl butoxide, and a "suffocation" product. BMC Dermatology, 10 6-1-6-7. doi:10.1186/1471-5945-10-6


Author Barker, Stephen C.
Altman, Phillip M.
Title A randomised, assessor blind, parallel group comparative efficacy trial of three products for the treatment of head lice - melalueca oil and lavender oil, pyrethrins and piperonyl butoxide, and a "suffocation" product
Journal name BMC Dermatology   Check publisher's open access policy
ISSN 1471-5945
Publication date 2010-08-20
Sub-type Article (original research)
DOI 10.1186/1471-5945-10-6
Open Access Status DOI
Volume 10
Start page 6-1
End page 6-7
Total pages 7
Place of publication London, United Kingdom
Publisher BioMed Central
Collection year 2011
Language eng
Formatted abstract
Background:
There are many different types of pediculicides available OTC in Australia. In this study we compare the efficacy and safety of three topical pediculicides: a pediculicide containing melaleuca oil (tea tree oil) and lavender oil (TTO/LO); a head lice "suffocation" product; and a product containing pyrethrins and piperonyl butoxide (P/PB).

Method:
This study was a randomised, assessor-blind, comparative, parallel study of 123 subjects with live head lice. The head lice products were applied according to the manufacturer's instructions (the TTO/LO product and the "suffocation" product were applied three times at weekly intervals according to manufacturers instructions (on Day 0, Day 7 and Day 14) and the P/PB product was applied twice according to manufacturers instructions (on Day 0 and Day 7)). The presence or absence of live lice one day following the last treatment was determined.

Results:
The percentage of subjects who were louse-free one day after the last treatment with the product containing tea tree oil and lavender oil (41/42; 97.6%) and the head lice "suffocation" product (40/41, 97.6%) was significantly higher compared to the percentage of subjects who were louse-free one day after the last treatment with the product containing pyrethrins and piperonyl butoxide (10/40, 25.0%; adj. p < 0.0001).

Conclusion:

The high efficacy of the TTO/LO product and the head lice "suffocation" product offers an alternative to the pyrethrins-based product.
© 1999-2011 BioMed Central Ltd
Keyword Lice infestations
Children
Insecticides
Treatment outcome
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article number 6.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Chemistry and Molecular Biosciences
 
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Created: Tue, 22 Mar 2011, 12:36:26 EST by Jennifer Falknau on behalf of School of Chemistry & Molecular Biosciences