Preventive strategies for ventilator associated pneumonia

Boots, Robert J., Udy, Andrew, Holley, Anthony and Lipman, Jeffrey (2010) Preventive strategies for ventilator associated pneumonia. Current Respiratory Medicine Reviews, 6 4: 238-252. doi:10.2174/157339810793563758

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Author Boots, Robert J.
Udy, Andrew
Holley, Anthony
Lipman, Jeffrey
Title Preventive strategies for ventilator associated pneumonia
Journal name Current Respiratory Medicine Reviews   Check publisher's open access policy
ISSN 1573-398X
Publication date 2010-11
Sub-type Critical review of research, literature review, critical commentary
DOI 10.2174/157339810793563758
Volume 6
Issue 4
Start page 238
End page 252
Total pages 15
Editor Ross Freebairn
Joseph Varon
Place of publication Bussum, Netherlands
Publisher Bentham Science Publishers
Collection year 2011
Language eng
Formatted abstract
Ventilator associated pneumonia (VAP) increases mortality and hospital length of stay, In addition, increased costs can be directly linked to the development of VAP in the critically ill. Significant variability exists in the incidence of VAP, which is not entirely accounted for by the variation in case-mix between intensive care units. Controversy exists regarding the need for bronchoscopic or other invasive diagnostic techniques compared to clinically based diagnosis. VAP occurs as a result of airway colonisation with pathogenic bacteria, aspiration into the distal airways and the progression of tracheobronchitis to pneumonia. Preventive measures involve strategies to prevent aspiration, limit the duration of mechanical ventilation and reduce the potential for contamination by ventilation equipment. Pharmacological prophylaxis and infection control procedures aim to reduce airway bacterial colonization. The introduction of protocolised strategies to reduce VAP with performance monitoring has shown efficacy in reducing this complication of mechanical ventilation.
© 2010 Bentham Science Publishers Ltd.
Keyword Ventilator associated pneumonia
Ventilator induced lung injury
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Special issue: "The Optimal Care of the Lung in the Critically Ill".

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2011 Collection
School of Medicine Publications
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Citation counts: Scopus Citation Count Cited 4 times in Scopus Article | Citations
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Created: Mon, 21 Mar 2011, 21:12:11 EST by Sia Athanasas on behalf of Anaesthesiology and Critical Care - RBWH