Partial replacement of tricuspid valve using cryopreserved homograft

Shrestha, Bishwo M.S., Fukushima, Satsuki, Vrtik, Marian, Chong, Ian H., Sparks, Lisa, Jalali, Homayoun and Pohlner, Peter G. (2010) Partial replacement of tricuspid valve using cryopreserved homograft. The Annals of Thoracic Surgery, 89 4: 1187-1194. doi:10.1016/j.athoracsur.2009.12.047


Author Shrestha, Bishwo M.S.
Fukushima, Satsuki
Vrtik, Marian
Chong, Ian H.
Sparks, Lisa
Jalali, Homayoun
Pohlner, Peter G.
Title Partial replacement of tricuspid valve using cryopreserved homograft
Journal name The Annals of Thoracic Surgery   Check publisher's open access policy
ISSN 0003-4975
1552-6259
Publication date 2010-04
Sub-type Article (original research)
DOI 10.1016/j.athoracsur.2009.12.047
Volume 89
Issue 4
Start page 1187
End page 1194
Total pages 8
Place of publication Philadelphia, PA, United States
Publisher Elsevier
Collection year 2011
Language eng
Formatted abstract
Background: The optimal choice of prosthesis for tricuspid valve (TV) replacement is yet to be determined. Partial replacement of the TV using a homograft atrioventricular valve might offer resistance to infection, good durability, and excellent functionality, in addition to avoiding prosthesis-related morbidity.
Methods: We present 14 patients who underwent replacement of the TV using a homograft between 1997 and 2008. The mean age at operation was 32 years, including 5 patients younger than the age of 10. All patients preoperatively showed severe TV regurgitation as a result of active infective endocarditis in 5 patients, Ebstein anomaly in 4 patients, other cardiac anomalies in 4 patients, and rheumatic valvular disease in 1 patient. The TV homograft was used in 13 patients, and mitral homograft was used in 1 patient. Eleven patients had replacement of one leaflet only, whereas 3 patients required replacement of two leaflets. Concomitant cardiac procedures were performed in 7 patients.
Results: No mortalities occurred during the average postoperative follow-up of 61 months (range, 12 to 126 months). Reoperation for TV regurgitation after TV repair with homograft was performed in 3 patients. The remaining 11 patients had minimal symptoms without reintervention for TV regurgitation.
Conclusions: Partial replacement of the TV using a homograft provided good hospital and mid-term outcomes. This strategy might be useful in active infective endocarditis and congenital TV disease. © 2010 The Society of Thoracic Surgeons.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
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Created: Thu, 17 Mar 2011, 12:07:45 EST by Debbie Banks on behalf of School of Medicine