Atrial versus ventricular cannulation for a rotary ventricular assist device

Timms, Daniel, Gregory, Shaun, Hsu, Po-Lin, Thomson, Bruce, Pearcy, Mark, McNeil, Keith, Fraser, John and Steinseifer, Ulrich (2010) Atrial versus ventricular cannulation for a rotary ventricular assist device. Artificial Organs, 34 9: 714-720. doi:10.1111/j.1525-1594.2010.01093.x

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Author Timms, Daniel
Gregory, Shaun
Hsu, Po-Lin
Thomson, Bruce
Pearcy, Mark
McNeil, Keith
Fraser, John
Steinseifer, Ulrich
Title Atrial versus ventricular cannulation for a rotary ventricular assist device
Journal name Artificial Organs   Check publisher's open access policy
ISSN 0160-564X
Publication date 2010-09
Sub-type Article (original research)
DOI 10.1111/j.1525-1594.2010.01093.x
Volume 34
Issue 9
Start page 714
End page 720
Total pages 7
Place of publication Geesthacht, Germany
Publisher Wiley-Blackwell Publishing
Collection year 2011
Language eng
Abstract The ventricular assist device inflow cannulation site is the primary interface between the device and the patient. Connecting these cannulae to either atria or ventricles induces major changes in flow dynamics; however, there are little data available on precise quantification of these changes. The objective of this investigation was to quantify the difference in ventricular/vascular hemodynamics during a range of left heart failure conditions with either atrial (AC) or ventricular (VC) inflow cannulation in a mock circulation loop with a rotary left VAD. Ventricular ejection fraction (EF), stroke work, and pump flow rates were found to be consistently lower with AC compared with VC over all simulated heart failure conditions. Adequate ventricular ejection remained with AC under low levels of mechanical support; however, the reduced EF in cases of severe heart failure may increase the risk of thromboembolic events. AC is therefore more suitable for class III, bridge to recovery patients, while VC is appropriate for class IV, bridge to transplant/destination patients. © 2010, Copyright the Authors. Artificial Organs © 2010, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.
Keyword Cannula
Ventricular assist device
Rotary blood pump
Heart failure
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Presented in part at the 17th Congress of the International Society for Rotary Blood Pumps, held October 1–3, 2009 in Singapore.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 9 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 17 Mar 2011, 11:34:27 EST by Debbie Banks on behalf of School of Medicine