Percutaneous management of aortic stenosis in high-risk patients

Layland, Jamie J., Bell, Brendan, Mullany, Dan and Walters, Darren L. (2010) Percutaneous management of aortic stenosis in high-risk patients. Medical Journal of Australia, 192 9: 520-525.

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Name Description MIMEType Size Downloads
Author Layland, Jamie J.
Bell, Brendan
Mullany, Dan
Walters, Darren L.
Title Percutaneous management of aortic stenosis in high-risk patients
Journal name Medical Journal of Australia   Check publisher's open access policy
ISSN 0025-729X
Publication date 2010-05-03
Sub-type Article (original research)
Volume 192
Issue 9
Start page 520
End page 525
Total pages 6
Place of publication Strawberry Hills, Nsw, Australia
Publisher Australasian Medical Publishing Company
Collection year 2011
Language eng
Formatted abstract
• As the population ages, the prevalence of aortic stenosis is increasing.
• There is an unmet clinical need for the treatment of aortic stenosis in high-risk patients, who are often older, frail and have multiple comorbidities.
• Percutaneous aortic valve replacement (PAVR) is a new and innovative technique for the management of high-risk patients with aortic stenosis.
• There are currently two devices under evaluation in clinical trials in Australia: the CoreValve ReValving System and the Edwards SAPIEN valve.
• These devices are generally deployed retrogradely, mainly transfemorally or via the subclavian artery or, less commonly, transapically.
• Initial experience has been encouraging, with good shortterm outcomes. However, there is a lack of long-term data.
• PAVR is presently only advocated for high-risk older patients with symptomatic aortic stenosis.
• Where PAVR lies in the treatment algorithm for aortic stenosis will be determined by randomised controlled trials, but for now it offers a genuine treatment alternative for high-risk patients.
Keyword Aortic stenosis
High-risk patients
Percutaneous aortic valve replacement (PAVR)
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Medicine Publications
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Created: Thu, 17 Mar 2011, 09:32:23 EST by Debbie Banks on behalf of Medicine - Prince Charles Hospital