Breast conservation therapy for invasive lobular carcinoma: The impact of lobular carcinoma in situ in the surgical specimen on local recurrence and axillary node status

Stolier, A.J., Barre, G., Bolton, J.S., Fuhrman, G.M. and Looney, S. (2004) Breast conservation therapy for invasive lobular carcinoma: The impact of lobular carcinoma in situ in the surgical specimen on local recurrence and axillary node status. American Surgeon, 70 9: 818-821.

Author Stolier, A.J.
Barre, G.
Bolton, J.S.
Fuhrman, G.M.
Looney, S.
Title Breast conservation therapy for invasive lobular carcinoma: The impact of lobular carcinoma in situ in the surgical specimen on local recurrence and axillary node status
Journal name American Surgeon   Check publisher's open access policy
ISSN 0003-1348
1555-9823
Publication date 2004-09
Sub-type Article (original research)
Volume 70
Issue 9
Start page 818
End page 821
Total pages 4
Place of publication Cumming, GA, United States
Publisher Southeastern Surgical Congress
Language eng
Abstract Forty patients undergoing breast-conserving therapy for invasive lobular carcinoma were studied for the volume of lobular carcinoma in situ (LCIS) in the surgical specimen and its relationship to the surgical margins. The pathology of all cases was reviewed for margin status as well as the volume of LCIS in the surgical specimen. Mean follow-up time was 67 months. There were no local recurrences despite the fact that 38 per cent of patients had close or involved margins. There was one cancer-related death. Increasing tumor size and moderate or extensive involvement of the surgical specimen with LCIS were found to be independent predictors of axillary node metastases. The volume of LCIS in the surgical did not appear to have an impact on local recurrence. This paper adds to the growing body of literature suggesting that in patients undergoing breast-conserving therapy, LCIS in the surgical margin does not impact the risk of local recurrence and therefore may not require reexcision for close or involved surgical margins.
Keyword Radiation-therapy
Cancer
Surgery
Component
Survival
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Mon, 14 Mar 2011, 10:52:46 EST