Selective management of patients with neutropenic enterocolitis using peritoneal lavage

Sauter, Edward R., Vauthey, Jean Nicolas, Bolton, John S. and Sardi, Armando (1990) Selective management of patients with neutropenic enterocolitis using peritoneal lavage. Journal of Surgical Oncology, 45 1: 63-67. doi:10.1002/jso.2930450115

Author Sauter, Edward R.
Vauthey, Jean Nicolas
Bolton, John S.
Sardi, Armando
Title Selective management of patients with neutropenic enterocolitis using peritoneal lavage
Journal name Journal of Surgical Oncology   Check publisher's open access policy
ISSN 0022-4790
Publication date 1990-09
Sub-type Article (original research)
DOI 10.1002/jso.2930450115
Volume 45
Issue 1
Start page 63
End page 67
Total pages 5
Place of publication Hoboken, NJ, United States
Publisher John Wiley & Sons
Language eng
Abstract Neutropenic enterocolitis is a symptom complex of fever, abdominal pain, distention, nausea, vomiting, diarrhea, and bloody stools occurring in a patient with a low neutrophil count and is most often seen in patients with acute leukemia after a course of chemotherapy. In most cases, neutropenic entercolotis is a self-limited condition, but complications of transmural intestinal necrosis and bowel perforation may occur in a small number of patients. Surgical management should be reserved for those patients with bowel wall necrosis of perforation; however, early identification of these patients is difficult. We report our experience with the use of diagnostic peritoneal lavage in three patients with the symptoms and signs of neutropenic enterocolitis. In each case, Gram's stain of lavage fluid revealed no evidence of polymicrobial contamination of the peritoneal cavity. All three patients were managed medically, with resolution of their abdominal symptoms. Peritoneal lavage is helpful in excluding bowel perforation and avoiding unnecessary surgical intervention in patients with neutropenic enterocolitis.
Keyword Chemotherapy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Article first published online: 19 July 2006.

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Created: Mon, 14 Mar 2011, 10:52:42 EST