An analysis of sestamibi-positive versus -negative patients with primary hyperparathyroidism

Parel, R. J., Bolton, J. S. and Fuhrman, G. M. (2001). An analysis of sestamibi-positive versus -negative patients with primary hyperparathyroidism. In: 69th Annual Meeting of the Southeastern Surgical Congress, New Orleans, LA United States, (1101-1104). 2-6 February 2001.

Author Parel, R. J.
Bolton, J. S.
Fuhrman, G. M.
Title of paper An analysis of sestamibi-positive versus -negative patients with primary hyperparathyroidism
Conference name 69th Annual Meeting of the Southeastern Surgical Congress
Conference location New Orleans, LA United States
Conference dates 2-6 February 2001
Journal name American Surgeon   Check publisher's open access policy
Publisher Southeastern Surgical Congress
Publication Year 2001
Sub-type Fully published paper
ISSN 0003-1348
1555-9823
Volume 67
Issue 11
Start page 1101
End page 1104
Total pages 3
Language eng
Abstract/Summary We performed this study to evaluate two patient groups with primary hyperparathyroidism depending on whether their abnormal gland(s) could be preoperatively imaged with sestamibi. Patients with primary hyperparathyroidism evaluated by preoperative sestamibi examination from January 1999 to June 2000 were divided into two groups depending on the ability of sestamibi to localize their disease. Records were reviewed to determine pre- and postoperative biochemical data, weight of the excised glands, and total operating room time. When the sestamibi imaging was positive a minimally invasive parathyroidectomy was performed; however, when sestamibi scanning was negative patients underwent a formal bilateral neck exploration. All 40 patients in the sestamibi-positive group and 17 of 18 patients in the sestamibi-negative group were cured of their primary hyperparathyroidism as a result of surgery. Sestamibi scanning with a minimally invasive parathyroidectomy shortens operating room time and is most effective when adenomas are large. The results of this study suggest that strategies to preoperatively increase the activity of adenomas may improve the sensitivity of sestamibi scan localization of parathyroid adenomas.
Keyword P-GLYCOPROTEIN
PARATHYROIDECTOMY
EXPLORATION
HYPERPLASIA
FAILURE
DISEASE
CHOICE
1990S
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Conference Paper
Collection: School of Medicine Publications
 
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Created: Mon, 14 Mar 2011, 20:51:28 EST