Long-term results of wide field brachytherapy as the sole method of radiation therapy after segmental mastectomy for T-is,T-1,T-2 breast cancer

King, T. A., Bolton, J. S., Kuske, R. R., Fuhrman, G. M., Scroggins, T. G. and Jiang, X. Z. (2000). Long-term results of wide field brachytherapy as the sole method of radiation therapy after segmental mastectomy for T-is,T-1,T-2 breast cancer. In: Annual Meeting of the American Society of Breast Surgeons, Charleston, SC, United States, (299-304). 13-16 April 2000. doi:10.1016/S0002-9610(00)00454-2


Author King, T. A.
Bolton, J. S.
Kuske, R. R.
Fuhrman, G. M.
Scroggins, T. G.
Jiang, X. Z.
Title of paper Long-term results of wide field brachytherapy as the sole method of radiation therapy after segmental mastectomy for T-is,T-1,T-2 breast cancer
Conference name Annual Meeting of the American Society of Breast Surgeons
Conference location Charleston, SC, United States
Conference dates 13-16 April 2000
Journal name American Journal of Surgery   Check publisher's open access policy
Publisher Elsevier
Publication Year 2000
Sub-type Fully published paper
DOI 10.1016/S0002-9610(00)00454-2
ISSN 0002-9610
1879-1883
Volume 180
Issue 4
Start page 299
End page 304
Total pages 5
Language eng
Abstract/Summary Background: We hypothesized that wide-field brachytherapy (BRT) after margin negative excision would result in complication rates, local recurrence rates, and cosmesis scores equivalent to external beam radiotherapy (ERT). Methods: Patients with T(is,1,2) tumors less than or equal to 4 cm, 0 to 3 positive axillary nodes, and negative inked surgical margins were entered prospectively into BRT phase I/II trial. Patients who met the eligibility criteria for BRT but were treated with ERT during the same time period were retrospectively identified as controls. A blinded panel of healthcare professionals graded cosmetic outcome. Results: Fifty patients with 51 breast cancers received BRT from January 1992 to October 1993. We identified 94 patients eligible for BRT but concurrently treated with ERT. At a median follow-up of 75 months, the two groups were similar for grade III treatment toxicities, local/regional recurrence rates, and cosmesis scores. Conclusions: For selected breast cancer patients undergoing breast-conserving therapy, BRT is an attractive alternative to ERT.
Keyword RANDOMIZED CLINICAL-TRIAL
COMPARING TOTAL MASTECTOMY
IRRADIATION FOLLOWING LUMPECTOMY
CARCINOMA IN-SITU
AXILLARY DISSECTION
CONSERVATIVE SURGERY
STAGE-I
CONSERVING THERAPY
LOCAL RECURRENCE
TUMOR BED
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Conference Paper
Collection: School of Medicine Publications
 
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Created: Mon, 14 Mar 2011, 20:50:39 EST