Percutaneous coronary angioscopy in patients with restenosis after coronary angioplasty

White, Christopher J., Ramee, Stephen R., Mesa, Juan E. and Collins, Tyrone J. (1991) Percutaneous coronary angioscopy in patients with restenosis after coronary angioplasty. Journal of the American College of Cardiology, 17 6: B46-B49.

Author White, Christopher J.
Ramee, Stephen R.
Mesa, Juan E.
Collins, Tyrone J.
Title Percutaneous coronary angioscopy in patients with restenosis after coronary angioplasty
Journal name Journal of the American College of Cardiology   Check publisher's open access policy
ISSN 0735-1097
Publication date 1991-05
Sub-type Article (original research)
Volume 17
Issue 6
Start page B46
End page B49
Total pages 4
Place of publication San Diego, CA, United States
Publisher Elsevier
Language eng
Abstract Percutaneous transluminal coronary angioscopy with a flexible steerable microangioscope was performed in five patients undergoing repeat angioplasty. Recurrent lesions were assessed by angioscopy before and after the angioplasty procedure. The most common surface morphology observed in these restenosis lesians was that of white unpigmented lesions consistent with the proliferation of fibrous tissue. Also noted during angioscopy was the presence or absence of thrombus or dissection in association with the lesions either before or after angioplasty. Filmy wisps of tissue, presumably intimal flaps, were commonly visualized after angioplasty. There were no complications related to angioscopy or angioplasty in these patients. The surface morphology of restenosis lesions appears to be different from that of primary atherosclerotic lesions. The lesions in these five patients with restenosis were generally white and fibrotic in appearance, as opposed to the pigmented yellow to yellow-brown lesions commonly seen in undilated atherosclerotic lesions. It was also noted that the presence of intracoronary thrombus was strongly associated with the clinical syndrome of unstable angina. These findings support the hypothesis that restenosis lesions are the result of a reparative process consisting of smooth muscle cell proliferation and fibrosis.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 16 times in Thomson Reuters Web of Science Article | Citations
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Created: Mon, 14 Mar 2011, 10:33:17 EST