Anewballoon-expandabletantalumcoilstent: Angiographicpatency and histologicfindings in an atherogenicswinemodel

White, Christopher J., Ramee, Stephen R., Banks, Alan K., Mesa, Juan E., Chokshi, Saurabh and Isner, Jeffrey M. (1992) Anewballoon-expandabletantalumcoilstent: Angiographicpatency and histologicfindings in an atherogenicswinemodel. Journal of the American College of Cardiology, 19 4: 870-876. doi:10.1016/0735-1097(92)90534-T


Author White, Christopher J.
Ramee, Stephen R.
Banks, Alan K.
Mesa, Juan E.
Chokshi, Saurabh
Isner, Jeffrey M.
Title Anewballoon-expandabletantalumcoilstent: Angiographicpatency and histologicfindings in an atherogenicswinemodel
Journal name Journal of the American College of Cardiology   Check publisher's open access policy
ISSN 0735-1097
1558-3597
Publication date 1992-03
Sub-type Article (original research)
DOI 10.1016/0735-1097(92)90534-T
Volume 19
Issue 4
Start page 870
End page 876
Total pages 7
Place of publication San Diego, CA, United States
Publisher Elsevier
Language eng
Formatted abstract
The angiographicpatency and histologic characteristics of anewballoon-expandabletantalumstent were studied after implantation intervals ranging from 1 to 32 weeks in atherogenic miniature swine peripheral and coronary arteries. Stents were placed in 34 arteries (10 coronary and 24 iliac arteries) in a total of 13 swine. Two swine died within 24 h of stent implantation. Follow-up angiography was performed before death was induced in 11 swine (8 coronary and 19 iliac arteries) and revealed 100% patency without evidence of lumen stenosis, thrombosis or migration of the stents. The neointimal thickening was maximal at 4 weeks after stent implantation and was at its minimum at 32 weeks after implantation with reendothelialization of the stents generally complete at that time.

An advantage of this balloon-expandable device is its inherent longitudinal flexibility. The coil configuration allowed the nondeployed stent to negotiate acute bends in coronary arteries to reach the site of implantation and also allowed the deployed stent to conform to the natural contour of tortuous coronary arteries. The tantalum device was remarkable for its radiographic visibility, which greatly aided its placement under fluoroscopic guidance. This study demonstrates this slent's ease of implantation, excellent patency rate and absence of restenosis due to neointimal proliferation for up to 8 months in this atherogenicswinemodel.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Mon, 14 Mar 2011, 10:32:09 EST