Clinical and hemodynamic determinants of left ventricular dimensions

Messerli, Franz H., Sundgaard-Riise, Kirsten, Ventura, Hector O., Dunn, Francis G., Oigman, Wille and Frohlich, Edward D. (1984) Clinical and hemodynamic determinants of left ventricular dimensions. Archives of Internal Medicine, 144 3: 477-481. doi:10.1001/archinte.1984.00350150061019

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Author Messerli, Franz H.
Sundgaard-Riise, Kirsten
Ventura, Hector O.
Dunn, Francis G.
Oigman, Wille
Frohlich, Edward D.
Title Clinical and hemodynamic determinants of left ventricular dimensions
Journal name Archives of Internal Medicine   Check publisher's open access policy
ISSN 2168-6106
Publication date 1984-03-01
Sub-type Article (original research)
DOI 10.1001/archinte.1984.00350150061019
Open Access Status File (Publisher version)
Volume 144
Issue 3
Start page 477
End page 481
Total pages 5
Place of publication Chicago, IL, United States
Publisher American Medical Association
Language eng
Abstract This study was designed to quantitate the influence of 20 clinical, hemodynamic, and volume determinants of left ventricular (LV) structure. Systemic hemodynamics, intravascular volume, and LV echocardiographic measurements were collected in a heterogeneous population of 171 patients. Stepwise multiple-regression analysis indicated that body weight and body-surface area were the most powerful determinants of LV chamber size, wall thickness, and muscle mass. Age, a pressure independent determinant of myocardial mass, had no influence on chamber size or LV function. Arterial pressure correlated best with the relative wall thickness and chamber volume. Intravascular volume was a major discriminator for chamber volume, LV mass, and velocity of circumferential fiber shortening. It is concluded that body weight, arterial pressure, intravascular volume, and age are each independent determinants of the LV dimension. Systolic pressure most closely correlated with relative wall thickness and thereby is the best predictor of degree of concentric LV hypertrophy.
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Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 82 times in Thomson Reuters Web of Science Article | Citations
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Created: Mon, 14 Mar 2011, 10:12:39 EST