Comparison of open transabdominal AAA repair with endovascular AAA repair in reduction of postoperative stress response

Salartash, K., Sternbergh, W. C., York, J. W. and Money, S. R. (2001). Comparison of open transabdominal AAA repair with endovascular AAA repair in reduction of postoperative stress response. In: 25th Annual Meeting of the Peripheral-Vascular-Surgery-Society, Toronto, ON, Canada, (53-59). 10 June 2000. doi:10.1007/BF02693801


Author Salartash, K.
Sternbergh, W. C.
York, J. W.
Money, S. R.
Title of paper Comparison of open transabdominal AAA repair with endovascular AAA repair in reduction of postoperative stress response
Conference name 25th Annual Meeting of the Peripheral-Vascular-Surgery-Society
Conference location Toronto, ON, Canada
Conference dates 10 June 2000
Journal name Annals of Vascular Surgery   Check publisher's open access policy
Place of Publication Philadelphia, PA, United States
Publisher Elsevier
Publication Year 2001
Sub-type Fully published paper
DOI 10.1007/BF02693801
ISSN 0890-5096
Volume 15
Issue 1
Start page 53
End page 59
Total pages 6
Language eng
Formatted Abstract/Summary
Operative intervention causes a necessary biologic response known as the hypermetabolic stress response. Less invasive operative procedures may cause fewer metabolic and endocrine derangements. To evaluate the metabolic and endocrine differences between endovascular and transperitoneal abdominal aortic aneurysm (AAA) repair, 10 patients underwent standard open repair (open group) and 10 patients underwent endovascular repair of AAA (endovascular group) with a modular bifurcated endograft. Blood samples were obtained prior to general anesthesia (baseline) and every 6 hr for a 24-hr period. Assays for hormones related to the postoperative stress response as well as retinol-binding protein were performed. Peak hormonal values are presented in relation to the baseline. Demographic analysis of the two groups showed that there were no significant differences in age or ASA classification. The open group had a 9.6-fold increase in epinephrine release, which was significantly higher than the 1.6-fold increase in the endovascular group (p < 0.05). Elevations in cortisol were also significantly higher in the open group. Early postoperative nutritional derangements, as reflected by the levels of retinol-binding protein, were far less in the endovascular group than in the open group. Endovascular AAA repair appears to be associated with a marked reduction in the hypermetabolic stress response and nutritional deterioration, compared to traditional open repair. This reduction in physiologic stress may have salutary effects on the incidence of postoperative medical morbidity.
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Conference Paper
Collection: School of Medicine Publications
 
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Created: Mon, 14 Mar 2011, 10:03:15 EST