Psychological, behavioral and biochemical risk factors for coronary artery disease among American and Italian male corporate managers

Fava, Maurizio, Littman, Andrew, Lamon-Fava, Stefania, Milani, Richard, Shera, David, MacLaughlin, Robert, Cassem, Edwin, Leaf, Alexander, Marchio', Bruno, Bolognesi, Erta and Guaraldi, Gian Paolo (1992) Psychological, behavioral and biochemical risk factors for coronary artery disease among American and Italian male corporate managers. American Journal of Cardiology, 70 18: 1412-1416. doi:10.1016/0002-9149(92)90291-6


Author Fava, Maurizio
Littman, Andrew
Lamon-Fava, Stefania
Milani, Richard
Shera, David
MacLaughlin, Robert
Cassem, Edwin
Leaf, Alexander
Marchio', Bruno
Bolognesi, Erta
Guaraldi, Gian Paolo
Title Psychological, behavioral and biochemical risk factors for coronary artery disease among American and Italian male corporate managers
Journal name American Journal of Cardiology   Check publisher's open access policy
ISSN 0002-9149
1879-1913
Publication date 1992-12
Sub-type Article (original research)
DOI 10.1016/0002-9149(92)90291-6
Volume 70
Issue 18
Start page 1412
End page 1416
Total pages 5
Place of publication Bridgewater, NJ, United States
Publisher Excerpta Medica
Language eng
Abstract Differences in psychological, behavioral and biochemical risk factors for coronary artery disease (CAD) among male corporate managers of 2 countries (United States and Italy), with very different age-specific rates of mortality for CAD were evaluated. In all, 129 American (mean age 43 ± 7 years) and 80 Italian (mean age 45 ± 7 years) managers volunteered to participate in this study. Each subject was administered several questionnaires assessing various psychological and behavioral risk factors for CAD, and all 129 Americans and 55 of 80 Italians had their blood drawn between 8:00 and 9:30 AM after overnight fasting for the measurement of plasma levels of dehydroepiandrosterone-sulfate (DHEA-S), total cholesterol, triglycerides, and apolipoproteins A-I and B. Italian managers reported significantly more cynicism and hostility, and less enjoyment in leisure activities than did American ones. Furthermore, 40 Italian (51%) and only 18 American (14%) managers were smokers (this difference being statistically significant). Although no significant differences were found in factors positively related with CAD (cholesterol, triglycerides and apolipoprotein B), there were clear differences in parameters inversely correlated with the incidence of CAD. Italian managers had significantly lower levels of plasma DHEA-S and apolipoprotein A-I than did American ones. In conclusion, this study found that Italian managers had a significantly more unhealthy psychological and behavioral profile than did American ones, and had lower levels of those biochemical parameters (apolipoprotein A-I and DHEA-S) thought to have a protective role against development of CAD.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Mon, 14 Mar 2011, 09:45:58 EST