The obesity paradox: Impact of obesity on the prevalence and prognosis of cardiovascular diseases

Artham, Surya M., Lavie, Carl J., Milani, Richard V. and Ventura, Hector O. (2008) The obesity paradox: Impact of obesity on the prevalence and prognosis of cardiovascular diseases. Postgraduate Medicine, 120 2: 34-41. doi:10.3810/pgm.2008.07.1788


Author Artham, Surya M.
Lavie, Carl J.
Milani, Richard V.
Ventura, Hector O.
Title The obesity paradox: Impact of obesity on the prevalence and prognosis of cardiovascular diseases
Journal name Postgraduate Medicine   Check publisher's open access policy
ISSN 0032-5481
1941-9260
Publication date 2008-07-01
Sub-type Article (original research)
DOI 10.3810/pgm.2008.07.1788
Volume 120
Issue 2
Start page 34
End page 41
Total pages 8
Place of publication Berwyn, PA, United States
Publisher JTE Multimedia
Language eng
Abstract Obesity has reached global epidemic proportions and is associated with numerous comorbidities such as hypertension (HTN), type 2 diabetes mellitus, dyslipidemia, certain cancers, and chronic kidney disease (CKD). Obesity, via its direct maladaptive effects on cardiac structure and through its impact on conventional risk factors, is strongly associated with cardiovascular (CV) diseases such as heart failure (HF) and coronary heart disease (CHD). Despite these adverse associations, numerous studies indicate an "obesity paradox" in that being overweight or obese is associated with a favorable prognosis in many patients with established CV disease, particularly in patients with HTN, HF, and CHD. This review summarizes the adverse effects of obesity on CV disease risk factors and its role in the genesis of HTN, HF, CHD, and the obesity paradox. It concludes with a discussion on the potential benefits of weight loss in these patient populations.
Keyword Obesity
Obesity paradox
Hypertension
Heart failure
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 43 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 55 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 14 Mar 2011, 19:22:05 EST