Newly diagnosed breast cancer patients choose bilateral mastectomy over breast-conserving surgery when testing positive for a BRCA1/2 mutation

Stolier, A. J. and Corsetti, R. L. (2005) Newly diagnosed breast cancer patients choose bilateral mastectomy over breast-conserving surgery when testing positive for a BRCA1/2 mutation. American Surgeon, 71 12: 1031-1033.

Author Stolier, A. J.
Corsetti, R. L.
Title Newly diagnosed breast cancer patients choose bilateral mastectomy over breast-conserving surgery when testing positive for a BRCA1/2 mutation
Journal name American Surgeon   Check publisher's open access policy
ISSN 0003-1348
1555-9823
Publication date 2005-12
Sub-type Article (original research)
Volume 71
Issue 12
Start page 1031
End page 1033
Total pages 3
Place of publication Cumming, GA, United States
Publisher Southeastern Surgical Congress
Language eng
Abstract In women diagnosed with breast cancer and testing positive for a BRCA1/2 mutation, decisions as to whether to undergo prophylactic risk-reduction surgery may differ from those women who test positive in a presymptomatic phase. Eighty-four women were identified who had undergone genetic testing at the time of breast cancer diagnosis. The study group consisted of 46 of these women who had initially undergone breast-conserving surgery. Eight patients (17.4%) tested positive for a mutation. Seven of the eight underwent bilateral prophylactic mastectomy prior to receiving radiation therapy. The only patient not undergoing bilateral mastectomy was awaiting liver transplant. Women who are candidates for breast-conserving surgery and who test positive for a breast cancer gene mutation choose mastectomy over surveillance.
Keyword PROPHYLACTIC SURGERY
OVARIAN-CANCER
DECISIONS
SURVEILLANCE
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Mon, 14 Mar 2011, 08:53:27 EST