Premalignant lesions of the anal margin

Beck, David E. and Fazio, Victor W. (1989) Premalignant lesions of the anal margin. Southern Medical Journal, 82 4: 470-474.

Author Beck, David E.
Fazio, Victor W.
Title Premalignant lesions of the anal margin
Journal name Southern Medical Journal   Check publisher's open access policy
ISSN 0038-4348
Publication date 1989-04
Sub-type Article (original research)
Volume 82
Issue 4
Start page 470
End page 474
Total pages 5
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Language eng
Abstract AB Premalignant lesions of the anal margin include Bowen's disease (intraepithelial squamous cell carcinoma) and Paget's disease (intraepithelial adenocarcinoma). Our experience includes 11 patients with perianal Paget's disease and 37 patients with perianal Bowen's disease treated from 1957 to 1986. The patients with perianal Paget's disease were older, had a higher incidence of invasive cancer, and had a worse prognosis than those with perianal Bowen's disease. The characteristic appearance of these lesions and their failure to respond to conventional therapy should lead the clinician to obtain a biopsy, which readily establishes the diagnosis. Our experience confirms that adequate evaluation followed by wide local excision is the appropriate therapy. Close follow-up is recommended to identify recurrence of the perianal disease or development of other malignancies.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 12 times in Thomson Reuters Web of Science Article | Citations
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Created: Mon, 14 Mar 2011, 08:45:27 EST