Self-reported loss of consciousness after head trauma does not predispose to hypopituitarism in an older population

Rabelink, N. M., Peeters, G. M. E. E., van Schoor, N. M., Drent, M. L. and Lips, P. (2011) Self-reported loss of consciousness after head trauma does not predispose to hypopituitarism in an older population. Journal of Head Trauma Rehabilitation, 26 1: 90-97. doi:10.1097/HTR.0b013e31820367b3


Author Rabelink, N. M.
Peeters, G. M. E. E.
van Schoor, N. M.
Drent, M. L.
Lips, P.
Title Self-reported loss of consciousness after head trauma does not predispose to hypopituitarism in an older population
Journal name Journal of Head Trauma Rehabilitation   Check publisher's open access policy
ISSN 0885-9701
Publication date 2011-01
Sub-type Article (original research)
DOI 10.1097/HTR.0b013e31820367b3
Volume 26
Issue 1
Start page 90
End page 97
Total pages 8
Place of publication Philadelphia, PA, U.S.A.
Publisher Lippincott Williams & Wilkins
Collection year 2012
Language eng
Formatted abstract
Objective: This population study examines the prevalence of hypopituitarism and low bone mineral density (BMD) in older persons reporting loss of consciousness after head trauma (HT).

Methods: Data from the Longitudinal Aging Study Amsterdam were used pertaining to 630 women (53 HT) and 533 men (63 HT). Subjects were asked whether they had ever had an HT with loss of consciousness. Linear regression analysis (adjusted for age, body mass index, chronic diseases, smoking, alcohol use, and gender) was performed to examine the association between HT and serum anteriory pituitary hormone levels, BMD, and quantative ultrasound measurements.

Results: Serum follicle stimulating hormone was significantly higher in males in the HT group (P = .05) than in the non-HT group. This difference was not found in women (P = .25). No other differences were observed in serum hormone levels between subjects with and without HT (P > .30). Also, no significant differences between the HT and non-HT group were found in BMD and quantitative ultrasound measurements.

Conclusion: A self-reported history of HT with loss of consciousness does not seem to increase the risk of hypopituitarism and lower BMD in an aging population.
Keyword Bone mineral density
Bone ultrasound
Craniocerebral trauma
Head trauma
Hypopituitarism
Pituitary
Traumatic brain injury
Brain-injury
Pituitary-function
High-risk
Prevalence
Stress
Dysfunction
Responses
Axis
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Publication date: January/February 2011. "This study is based on data from the Longitudinal Aging Study Amsterdam (LASA)".

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
School of Human Movement and Nutrition Sciences Publications
 
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Created: Sun, 13 Mar 2011, 00:12:13 EST