TiO2-modified macroporous silica foams for advanced enrichment of multi-phosphorylated peptides

Wan, Jingjing, Qian, Kun, Qiao, Liang, Wang, Yunhua, Kong, Jilie, Yang, Pengyuan, Liu, Baohong and Yu, Chengzhong (2009) TiO2-modified macroporous silica foams for advanced enrichment of multi-phosphorylated peptides. Chemistry - A European Journal, 15 11: 2504-2508. doi:10.1002/chem.200802079


Author Wan, Jingjing
Qian, Kun
Qiao, Liang
Wang, Yunhua
Kong, Jilie
Yang, Pengyuan
Liu, Baohong
Yu, Chengzhong
Title TiO2-modified macroporous silica foams for advanced enrichment of multi-phosphorylated peptides
Journal name Chemistry - A European Journal   Check publisher's open access policy
ISSN 0947-6539
Publication date 2009-03-02
Sub-type Article (original research)
DOI 10.1002/chem.200802079
Volume 15
Issue 11
Start page 2504
End page 2508
Total pages 5
Place of publication Germany
Publisher Wiley - V C H Verlag GmbH & Co. KGaA
Language eng
Formatted abstract
A study was conducted to demonstrate a technique for selective enrichment of multiple phosphorylated peptides by manipulating the surface chemistry of TiO2-modified macroporous ordered silica foams (Ti-MOSF-1). It was demonstrated that TiO2-modified MOSF material had a surface area and that its surface was rich in coordinatively unsaturated TiIV, providing for more abundant and selective binding sites for phosphopeptides. The pure and modified MOSFs were also characterized in detail to understand their material characteristics and phosphopeptide enrichment behaviors. Some aggregates associated with the formation of Ti nanocrystals were also observed on the surface of Ti-MOSF-3 after the TiO2 was modified three times. It was also demonstrated that the surface modification of MOSF and the incorporation of the TiO2 were essential for the phosphopeptide enrichment behaviors.
Keyword Enrichment
Macroporous
Peptides
Silica foams
Titanium
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
 
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Created: Fri, 11 Mar 2011, 12:53:28 EST by Mr Kun Qian on behalf of Aust Institute for Bioengineering & Nanotechnology