Trends in incidence of childhood cancer in Australia, 1983-2006

Baade, P. D., Youlden, D. R., Valery, P. C., Hassall, T., Ward, L., Green, A. C. and Aitken, J. F. (2010) Trends in incidence of childhood cancer in Australia, 1983-2006. British Journal of Cancer, 102 3: 620-626. doi:10.1038/sj.bjc.6605503


Author Baade, P. D.
Youlden, D. R.
Valery, P. C.
Hassall, T.
Ward, L.
Green, A. C.
Aitken, J. F.
Title Trends in incidence of childhood cancer in Australia, 1983-2006
Journal name British Journal of Cancer   Check publisher's open access policy
ISSN 0007-0920
1532-1827
Publication date 2010-02-02
Sub-type Article (original research)
DOI 10.1038/sj.bjc.6605503
Open Access Status DOI
Volume 102
Issue 3
Start page 620
End page 626
Total pages 7
Editor Nicole Muller-Berat Killman
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Collection year 2011
Language eng
Formatted abstract
Background: There are few population-based childhood cancer registries in the world containing stage and treatment data.

Methods: Data from the population-based Australian Paediatric Cancer Registry were used to calculate incidence rates during the most recent 10-year period (1997–2006) and trends in incidence between 1983 and 2006 for the 12 major diagnostic groups of the International Classification of Childhood Cancer.

Results: In the period 1997–2006, there were 6184 childhood cancer (at 0–14 years) cases in Australia (157 cases per million children). The commonest cancers were leukaemia (34%), that of the central nervous system (23%) and lymphomas (10%), with incidence the highest at 0–4 years (223 cases per million). Trend analyses showed that incidence among boys for all cancers combined increased by 1.6% per year from 1983 to 1994 but have remained stable since. Incidence rates for girls consistently increased by 0.9% per year. Since 1983, there have been significant increases among boys and girls for leukaemia, and hepatic and germ-cell tumours, whereas for boys, incidence of neuroblastomas and malignant epithelial tumours has recently decreased. For all cancers and for both sexes combined, there was a consistent increase (+0.7% per year, 1983–2006) at age 0–4 years, a slight non-significant increase at 5–9 years, and at 10–14 years, an initial increase (2.7% per year, 1983–1996) followed by a slight non-significant decrease.

Conclusion: Although there is some evidence of a recent plateau in cancer incidence rates in Australia for boys and older children, interpretation is difficult without a better understanding of what underlies the changes reported.
Keyword Cancer incidence
Paediatric
Childhood
Trends
Leukaemia
Lymphoma
Term-follow-up
Time trends
Children
Survivors
Sweden
Adolescents
Leukemia
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 56 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 60 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 09 Mar 2011, 15:34:18 EST by Geraldine Fitzgerald on behalf of Australian Centre for International and Tropical Health and Nutrition