Towards the identification of new markers of pancreatic cancer by gene expression analysis

Rosty, C. (2004) Towards the identification of new markers of pancreatic cancer by gene expression analysis. Bulletin du Cancer, 91 7-8: 593-598.

Author Rosty, C.
Title Towards the identification of new markers of pancreatic cancer by gene expression analysis
Language of Title fre
Journal name Bulletin du Cancer   Check publisher's open access policy
Language of Journal Name fre
ISSN 0007-4551
1769-6917
Publication date 2004-07
Sub-type Critical review of research, literature review, critical commentary
Volume 91
Issue 7-8
Start page 593
End page 598
Total pages 6
Place of publication Montrouge, France
Publisher John Libbey Eurotext
Language fre
Abstract The poor prognosis of pancreatic cancer has remained unchanged for many years, with a 5-year survival of less than 5%. Current methods for diagnosing pancreatic cancer are inadequate at identifying small tumors that can be resected by surgery. Characterization of gene expression patterns in pancreatic cancer provided a list of genes that are specifically overexpressed in cancer cells. These genes are putative novel markers for the diagnosis and the prognosis of pancreatic cancer and for the development of targeted therapies. Gene expression analysis should lead to the discovery of molecular markers for early detection of pancreatic cancer that could benefit patients at high risk of developping pancreatic cancer.
Keyword Pancreatic cancer
Gene expression
DNA microarray
Sage
Marker
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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Created: Wed, 09 Mar 2011, 14:22:09 EST