Serological evaluation of the 12 kDa subunit of antigen B in Echinococcus granulosus cyst fluid by immunoblot analysis

Leggatt, G. R., Yang, W. and McManus, D. P. (1992) Serological evaluation of the 12 kDa subunit of antigen B in Echinococcus granulosus cyst fluid by immunoblot analysis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 86 2: 189-192. doi:10.1016/0035-9203(92)90566-U


Author Leggatt, G. R.
Yang, W.
McManus, D. P.
Title Serological evaluation of the 12 kDa subunit of antigen B in Echinococcus granulosus cyst fluid by immunoblot analysis
Journal name Transactions of the Royal Society of Tropical Medicine and Hygiene   Check publisher's open access policy
ISSN 0035-9203
Publication date 1992-03
Sub-type Article (original research)
DOI 10.1016/0035-9203(92)90566-U
Volume 86
Issue 2
Start page 189
End page 192
Total pages 4
Language eng
Abstract This study evaluated the 12 kDa (smallest) subunit of Echinococcus granulosus antigen B as a diagnostic molecule. Using immunoblotting, 90.9% of cystic hydatid patients, 40% of alveolar hydatid patients and 5.5% of cysticercosis patients showed sero-reactivity to this subunit. Human antibody response to the 12 kDa molecule appeared independent of factors such as parasite strain or host population responsiveness. The majority of infection sera, and some normal human controls, also recognized the 38 kDa subunit of antigen 5.
Keyword HUMAN HYDATID-DISEASE
PROTEINS
ASSAY
GELS
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Diamantina Institute Publications
 
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Created: Wed, 09 Mar 2011, 13:01:21 EST