Bioenergetic characteristics of the costal and crural diaphragm in mammals

Hodge, Kelly, Powers, Scott K., Coombes, Jeff, Fletcher, Louise, Demirel, Haydar A., Dodd, Stephen L. and Martin, Daniel (1997) Bioenergetic characteristics of the costal and crural diaphragm in mammals. Respiration Physiology, 109 2: 149-154. doi:10.1016/S0034-5687(97)00051-0

Author Hodge, Kelly
Powers, Scott K.
Coombes, Jeff
Fletcher, Louise
Demirel, Haydar A.
Dodd, Stephen L.
Martin, Daniel
Title Bioenergetic characteristics of the costal and crural diaphragm in mammals
Journal name Respiration Physiology   Check publisher's open access policy
ISSN 0034-5687
Publication date 1997-08
Sub-type Article (original research)
DOI 10.1016/S0034-5687(97)00051-0
Volume 109
Issue 2
Start page 149
End page 154
Total pages 6
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Language eng
Formatted abstract
These experiments compared oxidative and glycolytic enzyme activity in the costal and cruraldiaphragm in seven adult mammals (mouse, rat, rabbit, ferret, sheep, pig, cow) ranging in body mass from approximately 0.03 to 422 kg. Segments of the costal and cruraldiaphragm from the aforementioned species were homogenized to determine the activities of the glycolytic enzyme, lactate dehydrogenase (LDH), and the Krebs cycle enzyme, citrate synthase (CS). The results indicated that metabolic differences between the costal and cruraldiaphragm do not exist in all mammalian species. Specifically, CS activity differed (P<0.05) between the costal and cruraldiaphragm (costal approximately 36% greater than crural) in only two species (rat and rabbit). Further, the oxidative capacity of the costal and cruraldiaphragm was significantly correlated with both breathing frequency and resting metabolic rate (r=0.92–0.57; P<0.05) across the species investigated. In contrast, glycolytic capacity was not significantly correlated (P>0.05) with either breathing frequency or resting metabolic rate.
Keyword Enzyme, oxidative vs. glycolytic, diaphragm
Mammals, comparative (seven species)
Muscle, diaphragm, enzyme activity
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Title since 2002: Respiratory Physiology and Neurobiology (1569-9048; 1878-1519)

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Human Movement and Nutrition Sciences Publications
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Created: Wed, 09 Mar 2011, 08:53:23 EST