Bone disease in analgesic nephropathy

Fassett, R. G., Lien, J. W. K., Mathew, T. H. and McClure, J. (1982) Bone disease in analgesic nephropathy. Clinical Nephrology, 18 6: 273-279.

Author Fassett, R. G.
Lien, J. W. K.
Mathew, T. H.
McClure, J.
Title Bone disease in analgesic nephropathy
Journal name Clinical Nephrology   Check publisher's open access policy
ISSN 0301-0430
Publication date 1982
Sub-type Article (original research)
Volume 18
Issue 6
Start page 273
End page 279
Total pages 7
Place of publication Oberhaching, Germany
Publisher Dustri-Verlag Dr. Karl Feistle
Language eng
Abstract Clinical, biochemical, radiological and bone biopsy findings were studied in 15 patients with end stage renal disease due to analgesic nephropathy and compared with data from age and sex matched controls who had end stage renal disease from other causes. Patients with analgesic nephropathy had significantly higher osteoid volume (P < 0.04), reduced calcification fronts (P < 0.001) and lower percentage mineralization (P < 0.04). Serum alkaline phosphatase was significantly higher in the analgesic group (P < 0.005). It is concluded that osteomalacia is more common and severe in the group of patients with end stage renal disease due to analgesic nephropathy. There was no relationship between osteomalacia and the duration of renal failure, acidosis, aluminium deposition or other serum biochemical abnormalities.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Human Movement and Nutrition Sciences Publications
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Created: Wed, 09 Mar 2011, 08:43:09 EST