Detection of glomerular bleeding by phase-contrast microscopy

Fassett, R. G., Horgan, B. A. and Mathew, T. H. (1982) Detection of glomerular bleeding by phase-contrast microscopy. Lancet, 319 8287: 1432-1434.

Author Fassett, R. G.
Horgan, B. A.
Mathew, T. H.
Title Detection of glomerular bleeding by phase-contrast microscopy
Journal name Lancet   Check publisher's open access policy
ISSN 0140-6736
Publication date 1982
Sub-type Article (original research)
Volume 319
Issue 8287
Start page 1432
End page 1434
Total pages 3
Place of publication London, United Kingdom
Publisher Lancet Publishing
Language eng
Abstract Midstream urine specimens from 303 consecutive patients with haematuria were examined with phase-contrast microscopy to determine whether the source of the haematuria could be predicted on the basis of urinary red-cell morphology. In 253 patients a definite diagnosis was made but the data for the other 50 were inadequate to allow a definite diagnosis. With phase-contrast microscopy in 120 patients (115 had proven glomerulonephritis and 5 had lesions of the lower urinary tract) and non-glomerular in 105 patients (100 had lesions of the lower urinary tract and 5 had proven glomerulonephritis). A mixed picture of glomerular and non-glomerular red cells was seen in 28 patients, most commonly in association with IgA nephropathy and renal calculi. The assessment of urinary red-cell morphology by means of phase-contrast microscopy can add importantly to clinical information and, together with the presence of red-cell casts and protein in the urine, can help the clinician decide on initial investigations in patients with haematuria.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Human Movement and Nutrition Sciences Publications
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Created: Wed, 09 Mar 2011, 08:42:56 EST