Assessing key safety concerns of a Wolbachia-based strategy to control dengue transmission by Aedes mosquitoes

Popovici, J, Moreira, LA, Poinsignon, A, Iturbe-Ormaetxe, I, McNaughton, D and O'Neill, SL (2010) Assessing key safety concerns of a Wolbachia-based strategy to control dengue transmission by Aedes mosquitoes. Memorias do Instituto Oswaldo Cruz, 105 8: 957-964. doi:10.1590/S0074-02762010000800002

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Author Popovici, J
Moreira, LA
Poinsignon, A
Iturbe-Ormaetxe, I
McNaughton, D
O'Neill, SL
Title Assessing key safety concerns of a Wolbachia-based strategy to control dengue transmission by Aedes mosquitoes
Formatted title
Assessing key safety concerns of a Wolbachia-based strategy to control dengue transmission by Aedes mosquitoes
Journal name Memorias do Instituto Oswaldo Cruz   Check publisher's open access policy
ISSN 0074-0276
1678-8060
Publication date 2010-12
Sub-type Article (original research)
DOI 10.1590/S0074-02762010000800002
Open Access Status DOI
Volume 105
Issue 8
Start page 957
End page 964
Total pages 8
Place of publication Rio de Janeiro, Brazil
Publisher Instituto Oswaldo Cruz
Collection year 2011
Language eng
Formatted abstract
Mosquito-borne diseases such as dengue fever, chikungunya or malaria affect millions of people each year and control solutions are urgently needed. An international research program is currently being developed that relies on the introduction of the bacterial endosymbiont Wolbachia pipientis into Aedes aegypti to control dengue transmission. In order to prepare for open-field testing releases of Wolbachia-infected mosquitoes, an intensive social research and community engagement program was undertaken in Cairns, Northern Australia. The most common concern expressed by the diverse range of community members and stakeholders surveyed was the necessity of assuring the safety of the proposed approach for humans, animals and the environment. To address these concerns a series of safety experiments were undertaken. We report in this paper on the experimental data obtained, discuss the limitations of experimental risk assessment and focus on the necessity of including community concerns in scientific research.
Copyright © 2010 - Instituto Oswaldo Cruz - Fiocruz.
Keyword Aedes aegypti
Wolbachia
Dengue
Risk assessment
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Biological Sciences Publications
 
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Created: Sun, 27 Feb 2011, 00:04:52 EST