Antimicrobial Peptides in Plants

Kaas, Quentin, Westermann, Jan-Christoph, Troeira Henriques, Sonia and Craik, David J. (2010). Antimicrobial Peptides in Plants. In Guangshun Wang (Ed.), Antimicrobial Peptides: Discovery, Design, and Novel Therapeutic Strategies (pp. 40-71) Wallingford, Oxfordshire, UK: CAB International. doi:10.1079/9781845936570.0040

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Author Kaas, Quentin
Westermann, Jan-Christoph
Troeira Henriques, Sonia
Craik, David J.
Title of chapter Antimicrobial Peptides in Plants
Title of book Antimicrobial Peptides: Discovery, Design, and Novel Therapeutic Strategies
Place of Publication Wallingford, Oxfordshire, UK
Publisher CAB International
Publication Year 2010
Sub-type Research book chapter (original research)
DOI 10.1079/9781845936570.0040
Series Advances in Molecular and Cellular Microbiology 18
ISBN 9781845936570
Editor Guangshun Wang
Chapter number 3
Start page 40
End page 71
Total pages 32
Total chapters 12
Collection year 2011
Language eng
Formatted Abstract/Summary
This chapter provides an overview of plant antimicrobial peptides. It mainly focuses on  one particular class of plant defence peptides, namely the cyclotides, which have been discovered over the last decade in plants from the Rubiaceae, Violaceae and Cucurbitaceae families. Cyclotides have a head-to-tail cyclized peptide backbone and a cystine knot motif formed from their six conserved cysteine residues, which makes them exceptionally stable. This chapter describes their isolation and characterization, structure and biosynthesis, and applications. The structural stability of cyclotides makes them excellent scaff olds for the engineering of novel therapeutic proteins. Advances in methods for the production of cyclotides and their potential clinical applications are also described.
Keyword Antimicrobial Peptides
Q-Index Code B1
Q-Index Status Confirmed Code
Institutional Status UQ

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Created: Thu, 24 Feb 2011, 12:33:32 EST by Susan Allen on behalf of Institute for Molecular Bioscience