Biodiversity and biogeography of phages in modern stromatolites and thrombolites

Desnues, Christelle, Rodriguez-Brito, Beltran, Rayhawk, Steve, Kelley, Scott, Tran, Tuong, Haynes, Matthew, Liu, Hong, Furlan, Mike, Wegley, Linda, Chau, Betty, Ruan, Yijun, Hall, Dana, Angly, Florent E., Edwards, Robert A., Li, Linlin, Thurber, Rebecca Vega, Reid, R. Pamela, Siefert, Janet, Souza, Valeria, Valentine, David L., Swan, Brandon K., Breitbart, Mya and Rohwer, Forest (2008) Biodiversity and biogeography of phages in modern stromatolites and thrombolites. Nature, 452 7185: 340-343. doi:10.1038/nature06735

Author Desnues, Christelle
Rodriguez-Brito, Beltran
Rayhawk, Steve
Kelley, Scott
Tran, Tuong
Haynes, Matthew
Liu, Hong
Furlan, Mike
Wegley, Linda
Chau, Betty
Ruan, Yijun
Hall, Dana
Angly, Florent E.
Edwards, Robert A.
Li, Linlin
Thurber, Rebecca Vega
Reid, R. Pamela
Siefert, Janet
Souza, Valeria
Valentine, David L.
Swan, Brandon K.
Breitbart, Mya
Rohwer, Forest
Title Biodiversity and biogeography of phages in modern stromatolites and thrombolites
Journal name Nature   Check publisher's open access policy
ISSN 0028-0836
Publication date 2008-03-20
Sub-type Article (original research)
DOI 10.1038/nature06735
Volume 452
Issue 7185
Start page 340
End page 343
Total pages 4
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Language eng
Formatted abstract
Viruses, and more particularly phages (viruses that infect bacteria), represent one of the most abundant living entities in aquatic and terrestrial environments. The biogeography of phages has only recently been investigated and so far reveals a cosmopolitan distribution of phage genetic material (or genotypes)1, 2, 3, 4. Here we address this cosmopolitan distribution through the analysis of phage communities in modern microbialites, the living representatives of one of the most ancient life forms on Earth. On the basis of a comparative metagenomic analysis of viral communities associated with marine (Highborne Cay, Bahamas) and freshwater (Pozas Azules II and Rio Mesquites, Mexico) microbialites, we show that some phage genotypes are geographically restricted. The high percentage of unknown sequences recovered from the three metagenomes (>97%), the low percentage similarities with sequences from other environmental viral (n = 42) and microbial (n = 36) metagenomes, and the absence of viral genotypes shared among microbialites indicate that viruses are genetically unique in these environments. Identifiable sequences in the Highborne Cay metagenome were dominated by single-stranded DNA microphages that were not detected in any other samples examined, including sea water, fresh water, sediment, terrestrial, extreme, metazoan-associated and marine microbial mats. Finally, a marine signature was present in the phage community of the Pozas Azules II microbialites, even though this environment has not been in contact with the ocean for tens of millions of years. Taken together, these results prove that viruses in modern microbialites display biogeographical variability and suggest that they may be derived from an ancient community.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
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School of Chemistry and Molecular Biosciences
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Created: Mon, 21 Feb 2011, 14:30:36 EST