Human exposure to brominated flame retardants

Toms, Lisa-Maree, L., Hearn, Laurence, Sjodin, Andreas and Mueller, Jochen F. (2011). Human exposure to brominated flame retardants. In Ethel Eljarrat and Damià Barceló (Ed.), Brominated flame retardants (pp. 203-239) Berlin, Heidelberg, Germany: Springer-Verlag. doi:10.1007/698_2010_90


Author Toms, Lisa-Maree, L.
Hearn, Laurence
Sjodin, Andreas
Mueller, Jochen F.
Title of chapter Human exposure to brominated flame retardants
Title of book Brominated flame retardants
Place of Publication Berlin, Heidelberg, Germany
Publisher Springer-Verlag
Publication Year 2011
Sub-type Research book chapter (original research)
DOI 10.1007/698_2010_90
Series Handbook of Environmental Chemistry
ISBN 9783642192685
3642192688
Editor Ethel Eljarrat
Damià Barceló
Volume number 16
Start page 203
End page 239
Total pages 37
Total chapters 9
Collection year 2012
Language eng
Formatted Abstract/Summary
Human polybrominated diphenyl ether (PBDE) exposure occurs through a range of pathways including: ingestion of dust including hand-to-mouth contact; inhalation (air/particulate matter); and ingestion via food including the unique nutrition sources of human milk and placental transfer. While inhalation has been deemed a minor source of exposure, ingestion of food and dust make greater contributions to overall PBDE body burden with intake via dust reported to be much higher in infants than in adults. PBDEs have been detected in samples of human milk, blood serum, cord blood, and adipose tissue worldwide. Concentrations have been found to be highest in populations from North America, followed by Australia, Europe, and Asia. While factors such as gender and parity may not affect concentrations, occupational exposure and age (infants and children) are associated with higher PBDE concentrations.
In contrast to “traditional” persistent organic pollutants, there is an inverse relationship between PBDE body burden and age. Predicted body burden calculated using available information on intake and elimination rates of BFRs appears to underestimate measured human body burden data obtained through analysis of BFRs in blood or human milk. This may be due to unknown exposure or inaccurate elimination data. Further exposure studies should focus on younger age groups and an investigation of human PBDE half-lives.
© Springer-Verlag Berlin Heidelberg 2010
Keyword Adipose tissue
Blood
Body burden
Exposure
Half-lives
Human milk
Q-Index Code B1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Created: Fri, 11 Feb 2011, 13:53:45 EST by Mr Laurence Hearn on behalf of National Res Centre For Environmental Toxicology